Journal Publications
Conference Publications
Research Projects
PhD Research Supervised
Awards & Honours
Organo-catalyzed C-H bond activation / Transition metal-catalysed C―C & C―N bond formation, Exploration with special emphasis by the use of cheaper transition metals., Design & development of new metal-ligand catalyst systems for direct arylation reactions., Further investigation in cross coupling, hydroarylations, Cyclization and addition reactions., Development of New Synthetic Methodologies. Total synthesis of biologically active Natural Products/Drugs/Therapeutics., Asymmetric catalysis / Synthesis: Development of catalytic asymmetric reactions., Design and development of new metallo-catalyst and organo-catalysts., Medicinal chemistry, drug discovery & process development., Mechanism/target/structure-based drug discovery, lead generation and lead optimization., Particularly in the field of novel antimalarials, antitubercular, antimicrobials, anticancer agents, Antioxidant and antiplatelet agents, anti-influenza and psychoactive (CNS) agents., Green chemistry: Application of microwave-assisted/ ultrasound-assisted organic transformations..
Ph.D: [CSIR-CDRI,Lucknow & JNU,New Delhi];Postdoc from USA and Japan: 4 yrs 9 months (including JSPS; Completed Sponsored projects- 10; & ongoing project:02 (01 new ICMR sanctioned); Projects as Host Mentor: 04(Completed); Organized 01 International Conference & 02 CDP; 58 International Publications & 02 Patents; 63 Int. Conference Proceedings; 10 Workshops; 36 Invited lectures & 03 Plenary/Keynote lecture/session chaired; Established OMC lab; Postdoc’s Supervision: 04; Ph.D Supervision: 05(Completed) & 04(Ongoing); M.Sc Dissertation: 24(Completed); Research Training:11; For more Details, plz visit my webpage.
| Title | Total Outlay (In Lacs) |
Year | Funding Agency | Role |
|---|---|---|---|---|
| Exploring the immunomodulatory activities of novel Toll-like receptor-signaling inhibitors in peripheral blood mononuclear cells from lupus patients- A study to identify TLRs as drug targets for lupus | 67.81 | 2020-2023 | Core Research Grant SERB New Delhi | PI |
| Nitrogen and Oxygen containing heterocycles in the synthesis of drugs - From research to practice | 45.00 | 2019-2022 | Ministry of Education and Science, Perm, Russian Federation | PI |
| Strategic Investigation of Organocatalyzed Direct sp2 C-H Arylation methodology on Antimalarial lead Cassiarin F Alkaloids- A Potential Chemotherapeutic approach towards Antimalarial Drug Development. | 23.80 | 2019-2020 | NPIU, TEQIP III, New Delhi | PI |
| Small Molecule Fluorescent Probes for amyloid-beta for the detection of Alzheimer’s disease. | 18.30 | 2019-2020 | NPIU, TEQIP III, New Delhi | PI |
| Synthesis of hetero-substituted amino acids via C (sp3)-H functionalization and its applications | 33.17 | 2016-2019 | SERB-DST, New Delhi | PI |
| Strategic Investigation of Novel Pincer-Based metal-catalyzed sp2 and sp3 C-H bond activation reactions- Application towards the synthesis of Novel Bioheterocycles | 19.20 | 2016-2018 | SERB-DST, New Delhi | PI |
| Development of innovative Indigenous knowledge system (IKS)-based new cosmetic raw material- Isolation, extraction and chemical profiling of melanin biosynthesis pathways-based natural compounds | 33.36 | 2016-2020 | DST-NRF Indo- South Africa Joint Research Project, New Delhi | PI |
| Exploring Antimalarial Peroxides from Bench-side to Bed-side- Synthesis, Chemistry, Antimalarial Assessment and SAR studies of Novel functionalized 1, 2, 4-Trioxanes and 1, 2, 4, 5-Tetraoxanes | 14.50 | 2015-2018 | DST-ARRS Indo-Slovenian Joint Research Project, New Delhi | PI |
| Organizing International Conference - “Current Challenges in Drug Discovery Research (CCDDR 2015)” | 0.75 | 2015-2015 | DST, New Delhi | PI |
| Exploring non-opioid analgesics from bench-side to bed-side - An efficient, cost-effective, asymmetric synthesis and SAR study of new non-opioid anti-pain lead compound, Conolidine | 25.00 | 2014-2017 | SERB-DST | PI |
| Strategic investigation of organo-catalyzed direct arylation of arenes and hetero-arenes via sp2 C-H bond activation- Application to an efficient synthesis of bioactive heterocycles | 25.00 | 2014-2017 | Council of Scientific and Industrial Research (CSIR), New Delhi | PI |
| Exploring nitrogen-based heterocycles from bench-side to bed-side- Synthesis, chemistry, stereo-chemical assignment, structure-activity relationship studies and biological evaluation | 27.50 | 2014-2016 | DST-RFBR Indo-Russian Joint Research Project, New Delhi | PI |
| Chemo- and regio-selective transition metal-catalyzed asymmetric hydroarylation of methylenecyclobutanes and methylenecyclopentanes | 16.00 | 2013-2016 | MNIT Jaipur (Institute Seed Grant) | PI |
| Geotechnical investigation for proposed RCC ESRs (ESR capacity, 275KL/18m, 175/18m at Dantaramgarh, 350KL/18m at Narodada & Chudimiyan, 375KL/18M at Jajod, | 3.25 | 2013-2013 | Public Health Engineering Department, Government of Rajasthan | Co-PI |
| SNo. | Type | Title | Event | Place | Schedule |
|---|---|---|---|---|---|
| 1 | Talk | Transition-Metal-Free/Oxidant-Promoted C(sp2)-H Bond Activation/ Functionalization Reactions: Chemistry and Practical Approaches towards Bioactive Heterocycles | Virtual International Conference on Emerging Trends in Medicinal Chemistry–2021’ (ETMC-2021) | Department of Chemistry, S. V. National Institute of Technology (SV NIT), Surat | Mar-2021 |
| 2 | Talk | Learning and Teaching Online in Indian Education System During Covid-19 Pandemic- An Overview | V Prikamsky congress of Chemistry Teachers “Continuous chemical education- trends and directions of developments” | Faculty of Chemistry, Perm State University, Perm, Russia | Nov-2020 |
| 3 | Talk | Metal-Free, Oxidant-Promoted, Csp2-Csp3 Cross-Dehydrogenative Coupling- Chemistry and its Practical Application | All-Russian Scientific Conference with International Participation on “Organic Chemistry for Agriculture and Medicine” | Faculty of Chemistry, Department of Organic Chemistry, Perm State University, Perm, Russia | Oct-2020 |
| 4 | Keynote | Organocatalysis in C(sp2) -H Bond Activation Reactions- Chemistry and Applications to the Synthesis of Bioactive Heterocycles | All-Russian Scientific Conference with International Participation on “Organic Chemistry for Agriculture and Medicine” | Faculty of Chemistry, Department of Organic Chemistry, Perm State University, Perm, Russia | Oct-2020 |
| 5 | Talk | Organocatalyzed Decarboethoxy C-N Bond Formation- Application to the Synthesis of Indolo[2,1-a]isoquinoline and Dibenzopyrrocolone Alkaloids | All-Russian Scientific Conference with International Participation on “Organic Chemistry for Agriculture and Medicine” | Faculty of Chemistry, Department of Organic Chemistry, Perm State University, Perm, Russia | Oct-2020 |
| 6 | Talk | C-3 Tethered isobenzofuran-1(3H)-ones and ortho-Substituted-1H-isochromen-1-ones as Potent Antioxidant and Antiplatelet Agents- Design, Synthesis, Biological Evaluation, SAR and in silico Studies | Special Lecture Series as part of Agreement no. C- 26/174.5 of January 31, 2019 with the Ministry of Education and Science of the Perm Krai Territory, Russian Federation as per MOU (MNIT-PGNIU), Perm | Faculty of Chemistry, Department of Organic Chemistry, Perm State University, Perm, Russia | Oct-2020 |
| 7 | Talk | Novel C-Homoaporphine Analogues- Synthesis, Chemistry, Bioevaluation and their Structure-Activity Relationship studies | Special Lecture Series as part of Agreement no. C- 26/174.5 of January 31, 2019 with the Ministry of Education and Science of the Perm Krai Territory, Russian Federation as per MOU (MNIT-PGNIU), Perm | Faculty of Chemistry, Department of Organic Chemistry, Perm State University, Perm, Russia | Oct-2020 |
| 8 | Talk | Microwave-Assisted Synthesis of C8-Substituted Methylxanthines via Cross-Dehydrogenative Coupling (CDC) Strategy- Synthesis, Chemistry, Bioevaluation and their Practical Applications | Special Lecture Series as part of Agreement no. C- 26/174.5 of January 31, 2019 with the Ministry of Education and Science of the Perm Krai Territory, Russian Federation as per MOU (MNIT-PGNIU), Perm | Faculty of Chemistry, Department of Organic Chemistry, Perm State University, Perm, Russia | Oct-2020 |
| 9 | Talk | Novel Functionalized 1,2,4-Trioxanes as Antimalarial and Anticancer agents- Synthesis, Chemistry, Bioevaluation, SAR and in silico studies | Special Lecture Series as part of Agreement no. C- 26/174.5 of January 31, 2019 with the Ministry of Education and Science of the Perm Krai Territory, Russian Federation as per MOU (MNIT-PGNIU), Perm | Faculty of Chemistry, Department of Organic Chemistry, Perm State University, Perm, Russia | Oct-2020 |
| 10 | Talk | 2,3-Bis-(2-pyridyl)Pyrazine as an Efficient Organocatalyst for the Direct C(sp2)-H Arylation of Unactivated Arenes/Heteroarenes | Special Lecture Series as part of Agreement no. C- 26/174.5 of January 31, 2019 with the Ministry of Education and Science of the Perm Krai Territory, Russian Federation as per MOU (MNIT - PGNIU) | Faculty of Chemistry, Department of Organic Chemistry, Perm State University, Perm, Russia | Oct-2020 |
| 11 | Talk | Transition Metal-Free Direct Coupling of Aldehydes with Terminal Alkynes- An Efficient Process for the Synthesis of Pharmaceutically Privileged α, β-Unsaturated Ketones and Propargylic Alcohols | Special Lecture Series as part of Agreement no. C- 26/174.5 of January 31, 2019 with the Ministry of Education and Science of the Perm Krai Territory, Russian Federation as per MOU (MNIT - PGNIU) | Faculty of Chemistry, Department of Organic Chemistry, Perm State University, Perm, Russia | Oct-2020 |
| 12 | Talk | Metal-Free C-H Bond Activation Reactions- Approach to Access Bioactive Heterocycles via Modifying Guareschi-Thorpe & Favorskii Reactions | International Conference on “Frontier Areas of Chemistry (ICFAC) 2020” | Department of Chemistry, School of Physical Sciences, Mahatma Gandhi Central University, Bihar | Feb-2020 |
| 13 | Keynote | Artemisinin, a Nobel Medicine- A Booming Drug in Antimalarial Chemotherapy | 4th International Conference on Pharmacy and Pharmaceutical Sciences 2019 with the Theme: “Innovative Approaches, analysis and Developments in Pharmacy and Pharmaceutical Science” (4th ICPPS, 2019 | Bangkok, Thailand | Dec-2019 |
| 14 | Talk | Medicinal Chemistry- Basic Concepts and Applications in Drug Discovery | Special Seminar | Department of Chemistry, Kanoria PG Mahila Mahavidhyalaya, Jaipur, Rajasthan, India | Sep-2019 |
| 15 | Talk | Exploration of natural product inspired bioactive heterocycles from bench-side to bed-side- A journey towards drug discovery and development. | Department Seminar Series | Faculty of Chemistry, Department of Organic Chemistry, Perm State University, Perm, Russia | May-2019 |
| 16 | Talk | Development of Organocatalyzed sp2 C-H bond activation reactions- Synthesis, Chemistry, Scope and its practical applications | Department Seminar Series | Faculty of Chemistry, Department of Organic Chemistry, Perm State University, Perm, Russia | May-2019 |
| 17 | Keynote | Indian education system: An overview | IV Prikamsky congress of Chemistry Teachers “Continuous chemical education- trends and directions of developments” | Perm State University, Perm, Russia | May-2019 |
| 18 | Talk | Ag2O nanoparticle-catalyzed substrate-controlled regioselectivities- Direct access to bioactive 3-ylidenephthalides and isocoumarins | International Conference on “Polycarbonyl compounds 2019 dedicated to the 85th anniversary of Yu. S. Andrejchikov” | Faculty of Chemistry, Department of Organic Chemistry, Perm State University, Perm, Russia | May-2019 |
| 19 | Keynote | Carbonyl compounds as universal synthetic precursors for the direct access to natural product inspired bioactive pyridine-based heterocycles | International Conference on “Polycarbonyl compounds 2019 dedicated to the 85th anniversary of Yu. S. Andrejchikov” | Faculty of Chemistry, Department of Organic Chemistry, Perm State University, Perm, Russia | May-2019 |
| 20 | Talk | Role of Chemistry in Drug Discovery: Current Scenario, Scope and Future Opportunities | Department Special Seminar | Faculty of Basic and Applied Science, Vivekananda Global University, Jaipur | Jan-2019 |
| 21 | Talk | Recent Development in Interdisciplinary Research in Chemical Sciences at Laboratory of Organic and Medicinal Chemistry, MNIT Jaipur | National Workshop on "MIND-MELD-How Interdisciplinary are you" | Manipal University, Jaipur | Jul-2017 |
| 22 | Talk | Transition metal-catalyzed/Organo-Catalyzed C-H Bond Activation/Functionalization- Scope and Applications | Department Seminar Series | Faculty of Chemistry and Chemical Technology, University of Ljubljana, Ljubljana, Slovenia | Dec-2016 |
| 23 | Keynote | Artemisinin Derived Stable Ozonides- Synthesis, Chemistry, X-ray studies, in vitro and in vivo Antitubercular activities, SAR and molecular docking studies | International Conference on “Current Trends in Chemical Sciences” | Department of Organic Chemistry, Perm State University, Perm, Russia | Oct-2016 |
| 24 | Talk | Recent developments in the Chemistry and Biology of Antimalarial drug Artemisinin | National Conference (OCSD-2016) on "Organic Chemistry in Sustainable Development: Recent Advances and Future Challenges" | Department of Chemistry, Birla Institute of Science and Technology (BITS) Pilani, Pilani, India | Aug-2016 |
| 25 | Talk | Carbon-Carbon Bond Forming Reactions: Classical vs Modern | Department Seminar Series | Department of Chemistry, Goa University, Goa, India | Mar-2016 |
| 26 | Talk | Recent Advances in Antimalarial Peroxide-based Natural Product, Artemisinin- A Nobel Medicine for Malaria | Department Seminar Series | Department of Chemistry, Birla Institute of Science and Technology (BITS) Pilani-Goa Campus, Goa, In | Mar-2016 |
| 27 | Talk | Recent Advances in Antimalarial Peroxide-based Chemotherapy for Malaria- Artemisinin, A Nobel Medicine | One Day Symposium (ETACS-2016) on "Emerging Trends in Applied Chemical Sciences (ETACS-2016)" | Department of Chemistry, School of Chemical Sciences and Pharmacy, Central University of Rajasthan | Mar-2016 |
| 28 | Talk | Wittig Reaction in Organic Synthesis | Eminent lecture series | Department of Chemistry, Alankar P.G. Girls College (Affiliated to University of Rajasthan), Jaipur, | Feb-2016 |
| 29 | Talk | Perspective and Challenges in Antimalarial Chemotherapy- Design and Synthesis of Novel Artemisinin Analogues as Antimalarials | 22nd ISCB International Conference (ISCBC-2016) on "Recent Trends in Affordable and sustainable Drug Discovery and Developments" | Uka Tarsadia University, Bardoli, Surat, India | Feb-2016 |
| 30 | Talk | Discovery of Artemisinin as Nobel Medicine- A Gift from Traditional Chinese Herb Artemisia Annua | Departmental Seminar Series | Department of Chemistry, Sardar Vallabhbhai National Institute of Technology, Surat, India | Feb-2016 |
| 31 | Talk | Artemisinin, an Nobel Medicine- Still Only Drug of Choice for the Treatment of Malaria | Departmental Seminar Series | Department of Chemistry, Mohanlal Sukhadia University, Udaipur, India | Feb-2016 |
| 32 | Talk | Stable Bio-active Novel Peroxides: Synthesis, Chemistry and their Biological Evaluation | Departmental Seminar Series during Slovenia visit | Department of Chemistry, University of Ljubljana, Ljubljana, Slovenia | Sep-2015 |
| 33 | Talk | Systematic Investigation of Bio-active Ozonides and Aza-Peroxides- Synthesis, Chemistry and their Biological Evaluation | Departmental Seminar Series during Slovenia Visit | Department of Physical and Organic Chemistry, Jožef Stefan Institute, Ljubljana, Slovenia | Sep-2015 |
| 34 | Talk | Synthesis of Aza-heterocyclic compounds via transition metal-catalyzed direct arylation strategy | Departmental Seminar Series During Russia Visit | Department of Chemistry, Faculty of Chemistry, Perm State University, Perm, Russia | Mar-2015 |
| 35 | Talk | Synthesis, Chemistry and Bio-evaluation of Antimalarial Peroxide Drug Artemisinin | Departmental Seminar Series during Russia Visit | Department of organic Chemistry, Faculty of Chemistry, Perm State University, Perm, Russia | Mar-2015 |
| 36 | Talk | Direct catalytic asymmetric aldol reaction of thioamides - En route to Atorvastatin | 21st ISCB International Conference (ISCBC-2015) on "Current Trends in Drug Discovery and Developments (CTDDD)", 25th -28th Feb, 2015 | CSIR-Central Drug Research Institute, Lucknow, India | Feb-2015 |
| 37 | Talk | Artemisinin analogues- Synthesis, Chemistry and antimalarial assessment | UGC-Sponsored "National Conference on Current Trends in Chemical Sciences" NCCTCS 2014, 15th-16th Oct, 2014 | Department of Chemistry, St. Andrew’s College, Gorakhpur, India | Oct-2014 |
| 38 | Talk | Transition metal-catalyzed C-C bond formation via C-H bond activation- Versatility and practicality in natural product synthesis | Chemical Society (30th Oct, 2013) Popular Seminar Series | Department of Chemistry, St. Andrew’s College, Gorakhpur, India | Oct-2013 |
| 39 | Talk | Direct catalytic asymmetric aldol reaction of thioamides - An efficient route to Atorvastatin calcium (Lipitor) | Intra-Institute Conference (24th Feb, 2012) | Institute of Microbial Chemistry, Microbial Chemistry Research Foundation, Tokyo, Japan | Feb-2012 |
| S.No. | Category | Name of Activity | Organization | Place | Position | Schedule |
|---|---|---|---|---|---|---|
| 1 | International | 1st Visit to Perm State University, Russia as part of DST-RFBR Indo-Russian Joint Research Project | Perm State University | Perm, Russian Federation | Foreign Expert Researcher | Mar-2015 |
| 2 | International | 1st Visit to Slovenia as part of DST-ARRS Indo-Slovenia Joint Research Project | Jožef Stefan Institute | Ljubljana, Slovenia | Foreign Expert Researcher | Sep-2015 |
| 3 | International | Visit to Perm State University, Russia as part of DST-RFBR Indo-Russian Joint Research Project | Perm State University | Perm, Russian Federation | Foreign Expert Researcher | Oct-2016 |
| 4 | International | 2nd Visit to Slovenia as part of DST-ARRS Indo-Slovenia Joint Research Project | Jožef Stefan Institute | Ljubljana, Slovenia | Foreign Expert Researcher | Dec-2016 |
| 5 | International | Visit to Perm State University, Russia as part of MOU between MNIT Jaipur and PGNIU, Perm, Russian Federation | Perm State University | Perm, Russian Federation | Foreign Expert Scientist | May-2019 |